- Beta cells (in islets of Langerhans) then secretes insulin into the blood
- They target hepatocytes, muscles cells and other cells such as brain that have membrane bound receptors for insulin. Insulin binds to these receptors
- Adenyl cyclase is activated in each cell and converts ATP to cAMP
- this activates a series of enzyme reactions
- Glucose is converted into glycogen for storage/lipids
- or used in respiration
- glucose leave cells through specific channels
If blood glucose concentration is too low
- This change is detected by alpha cells (in islets of Langerhans)
- Alpha cells secrete the hormone glucagon
- Targets cells are heptocytes which posses specific receptors for glucagon
- glycogen is converted to glucose - glycogenolysis
- glucose is made from amino acids and lipids - gluconeogenesis
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